The described clinical case shows the challenges in the differential diagnosis of primary diffuse large B-cell lymphoma of the lung. It has been shown that the diagnosis can be made only by a morphological examination of a biopsy specimen, and the specimen should be representative and allow for full histological and immunohistochemical testing. A correct diagnostic algorithm, an interdisciplinary approach, the use of new technologies, particularly radiation imaging methods, to reliably

more »

... the primary localization and spread of the pathological process, biopsies for the morphological confirmation shorten the time to diagnosis. A quick diagnosis improves the treatment outcomes and affects the quality of life and life expectancy of patients.