Pathogenesis, Diagnosis, Treatment and Prevention Strategies of Human Coronavirus: A Review

Ayisha Shaukat, Muhammad Saqib Javed
2020 Bangladesh Journal of Infectious Diseases  
Coronaviruses is a group of virus which infects many species of animals, including humans. The rapid outbreak of COVID-19 raised serious attention at national and international levels and it was recognized as a pandemic by the World Health Organization. The disease model comprised of three different phases: replication of virus, hyperactivity of immune system and pulmonary cells destruction. For the diagnosis of asymptomatic carriers, viral nucleic acid (RNA) can be detected by using pharyngeal
more » ... swab. Isolation of infected persons prevents the transmission and spread risk of the disease. Therapy includes use of oxygen therapy, high-flow nasal cannula (HFNC) and methylprednisolone (IV) and in severe cases adrenaline (IV). Anti-viral drugs such as ritonavir plus lopinavir per-orally and antibiotics (moxifloxacin or any antibiotic) were administered by IM/IV route to prevent secondary bacterial infection. Education campaigns are launched to promote different precautionary measures to avoid disease transmission. Bangladesh Journal of Infectious Diseases, October 2020;7(suppl_2):S34-S37
doi:10.3329/bjid.v7i00.50160 fatcat:nn3fzpby4bhaflgbvuuouqfzs4