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Promoter Nucleosome Organization Shapes the Evolution of Gene Expression
2012
PLoS Genetics
Understanding why genes evolve at different rates is fundamental to evolutionary thinking. In species of the budding yeast, the rate at which genes diverge in expression correlates with the organization of their promoter nucleosomes: genes lacking a nucleosome-free region (denoted OPN for "Occupied Proximal Nucleosomes") vary widely between the species, while the expression of those containing NFR (denoted DPN for "Depleted Proximal Nucleosomes") remains largely conserved. To examine if early
doi:10.1371/journal.pgen.1002579
pmid:22438828
pmcid:PMC3305400
fatcat:2shzuuk5evap5pfj6nqkq34rrq