A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf
.
The ups and downs of biological timers
2005
Theoretical Biology and Medical Modelling
The need to execute a sequence of events in an orderly and timely manner is central to many biological processes, including cell cycle progression and cell differentiation. For self-perpetuating systems, such as the cell cycle oscillator, delay times between events are defined by the network of interacting proteins that propagates the system. However, protein levels inside cells are subject to genetic and environmental fluctuations, raising the question of how reliable timing is maintained. We
doi:10.1186/1742-4682-2-22
pmid:15967029
pmcid:PMC1208956
fatcat:awp2qzkvebf5tnlha724xdwwgu