Recent Development of Mono and Difluorination

1993 Journal of Synthetic Organic Chemistry, Japan  
is mainly classified into two types of reactions ; electrophilic and nucleophilic fluorinations . Preparations of monofluorinated compounds by the use of monofluorocarbene intermediates and monofluorinated building blocks are also summarized. Recent .development of difluorination via difluorocarbene, substituted difluoromethyl radicals , transformations of carbonyl and methylene groups to difluoromethylene group along with utilization of the difluoromethylated building blocks has been reviewed.
doi:10.5059/yukigoseikyokaishi.51.232 fatcat:7xy5adzdkbgfhnvlkahe6sl6ri