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In the past decade rapid advances of microarray technologies have made it possible to monitor the expression profiles of thousands of genes under various experimental conditions. The requirements for methods to handle such amounts of data have arisen. These massive source of information extracted from the genome project contain the keys to address fundamental problems relating to the prevention and cure of diseases, biological evolution mechanisms and the understanding of particular functionaldoi:10.1002/bmb.20588 pmid:22615226 fatcat:hdb3jwf4gbebhkxj4hgt7fl4qu