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mosaicFlye: Resolving long mosaic repeats using long error-prone reads
[article]
2020
bioRxiv
pre-print
Long-read technologies revolutionized genome assembly and enabled resolution of bridged repeats (i.e., repeats that are spanned by some reads) in various genomes. However the problem of resolving unbridged repeats (such as long segmental duplications in the human genome) remains largely unsolved, making it a major obstacle towards achieving the goal of complete genome assemblies. Moreover, the challenge of resolving unbridged repeats is not limited to eukaryotic genomes but also impairs
doi:10.1101/2020.01.15.908285
fatcat:nzfhvzk24factlkx4l66plepfy