Management of osteoarthritis of the knee

K. L. Bennell, D. J. Hunter, R. S. Hinman
2012 The BMJ (British Medical Journal)  
Osteoarthritis of the knee causes pain, limits activity, and impairs quality of life. Although it cannot be cured, advances in understanding and treatment have improved the outlook for people with this condition. This review will outline evidence for management and emphasise the importance of a patient centred multidisciplinary approach, conservative non-drug interventions, judicious use of drugs, and appropriate surgical referral. What is osteoarthritis and how common is it? Osteoarthritis is
more » ... Osteoarthritis is a painful chronic joint disease characterised by structural changes to the whole joint, including loss of articular cartilage, development of osteophytes, synovial inflammation, subchondral bone changes, meniscal damage, muscle weakness, and ligamentous laxity. It results from a complex interplay of genetic, metabolic, biomechanical, and biochemical factors. At the knee, osteoarthritis most commonly affects the medial tibiofemoral and patellofemoral joint compartments.
doi:10.1136/bmj.e4934 pmid:22846469 fatcat:orpvamk2xraavn7ui5r6ojwq5u