Visualizing the Heterogeneity of Effects in the Analysis of Associations of Multiple Myeloma with Glyphosate Use. Comments on Sorahan, T. Multiple Myeloma and Glyphosate Use: A Re-Analysis of US Agricultural Health Study (AHS) Data. Int. J. Environ. Res. Public Health 2015, 12, 1548–1559

Igor Burstyn, Anneclaire De Roos
2016 International Journal of Environmental Research and Public Health  
We address a methodological issue of the evaluation of the difference in effects in epidemiological studies that may arise, for example, from stratum-specific analyses or differences in analytical decisions during data analysis. We propose a new simulation-based method to quantify the plausible extent of such heterogeneity, rather than testing a hypothesis about its existence. We examine the contribution of the method to the debate surrounding risk of multiple myeloma and glyphosate use and
more » ... ose that its application contributes to a more balanced weighting of evidence.
doi:10.3390/ijerph14010005 pmid:28025514 pmcid:PMC5295256 fatcat:6efx4mqzezg37gs3435zvupiv4