which lodged the germ at some point in the excretory path. The latter was what produced the predominant cancers of the female sex, and was of subordinate importance in the male sex. It was quite conceivable that these might represent two species of cancer produced by different causes. Concerning the geographical distribution, there was a good deal of evidence to show the local specific prevalence of cancer. The distribution of cancer, like that of malaria, seemed to be governed by specific and

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... ot merely by general physical laws. Referring to Dr. Tatham's statistics that the increase in mortality from cancer in England was progressive, Dr. Payne remarked that that meant the rate of increase was itself increasing. Further, the rate of increase in cancer of the digestive organs was higher than the average for all organs. The most plausible explanation was the more abundant diet of the working classes, and the increased consumption of meat in England, but cancer was increasing in other countries where the economical conditions were not the same. It was disheartening to see that material prosperity possibly tended to favour the spread of cancer. Dr. MANDERS showed a case of abdominal tumour described as malignant in which improvement had resulted from the treatment by the high frequency current. Dr. LEESON (Twickenham) having addressed the meeting, The PRESIDENT in ashort speech summarized the points raised by the various speakers. He said they could not but feel that the day was not Jar off when they would obtain the means of preventing the incidence of cancer as they now could prevent an attack of the gout. MANCHESTER MEDICAL SOCIETY.-At a clinical meeting held on March igth, Dr. THOMAS HARRIS, President, in the chair, Mr. JOSEPH COLLIER showed the following surgical cases: (I) A man with excision of the left knee-joint for rheumatoid arthritis; (2) a boy with excision of the upper half of the fibula for central sarcoma; (3) a woman in whom the dilated and enlarged vermiform appendix had been adherent to and communicated with the bladder, so that faeces passed per urethram ; laparotomy had been performed and the appendix removed, the patient making a complete recovery; (4) a girl with erasion of the knee-joint, where the patella had been kept freely movable and the extensors had consequently retained full control over the joint.-Dr. JOSHTTA J. COX showed a boy, aged 7, and his sister, aged 9 years, both suffering from infantile myxoedema, and recovering rapidly under "thyroid treatment."