The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

David J Rotenberg, Qing Chang, Natalia Potapova, Andy Wang, Marcia Hon, Marcos Sanches, Nikola Bogetic, Nathan Frias, Tommy Liu, Brendan Behan, Rachad El-Badrawi, Stephen C Strother (+11 others)
2018 Frontiers in Neuroinformatics  
Investigations of mental illness have been enriched by the advent and maturation of neuroimaging technologies and the rapid pace and increased affordability of molecular sequencing techniques, however, the increased volume, variety and velocity of research data, presents a considerable technical and analytic challenge to curate, federate and interpret. Aggregation of high-dimensional datasets across brain disorders can increase sample sizes and may help identify underlying causes of brain
more » ... ction, however, additional barriers exist for effective data harmonization and integration for their combined use in research. To help realize the potential of multi-modal data integration for the study of mental illness, the Centre for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment-the CAMH Neuroinformatics Platform-based on the Ontario Brain Institute (OBI) Brain-CODE architecture, towards the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.
doi:10.3389/fninf.2018.00077 pmid:30459587 pmcid:PMC6232622 fatcat:ecbxaeuqtjhjlcqylhlkjb5qae