Quantification of aortic regurgitation and stroke volume by CMR - variation due to slice plane position. It matters where you measure!

Christian R Hamilton-Craig, Peter J Cawley, Abhishek Chaturvedi, Gregory J Wilson, William Kerwin, Catherine M Otto, Jeffrey H Maki
2011 Journal of Cardiovascular Magnetic Resonance  
Aortic regurgitation by CMR has been assessed in various locations, including sinus of valsalva (SOV), sinotubular junction (STJ), and ascending aorta (ASC). Variability in obtained measurements and interchangeability of these locations and methods in patients with varying valvular disease severity is unknown. We sought to determine the most appropriate aortic level for accurate phase contrast quantitative (Q) flow measurement of forward and backward flow and calculation of Qp:Qs in patients
more » ... h valvular heart disease. Methods and materials 57 patients with valvular disease (31 aortic regurgitation (AR), 25 mitral regurgitation (MR), 1 both) were imaged at 1.5T using Q flow at 3 ascending aorta locations: sinus of valsalva (SOV), sinotubular junction (STJ), tubular ascending aorta 1 cm above STJ (ASC). Pulmonary artery (PA) Q flow was performed at two adjacent locations 1 cm apart. No patient had intracardiac shunt. Blinded analysis was performed by two expert readers with SCMR level 2 and 3 experience. Net stroke volume (SV), forward volume (FV) and backward volume (BV) were measured and analyzed by Student t-test.
doi:10.1186/1532-429x-13-s1-p203 fatcat:vyfv3h2iuzc5raly55i7jo2qom