Synthesis of Enantiomeric Halolactones with Aromatic Ring, Their Anticancer Activity and Interactions with Biological Membranes

Witold Gładkowski, Aleksandra Pawlak, Aleksandra Włoch, Marcelina Mazur, Halina Kleszczyńska, Bożena Obmińska-Mrukowicz
2019 Proceedings (MDPI)  
Studying the effect of chirality on the activity of tested compounds, we synthesized new series of the enantiomeric (ee = 98–100%) β-aryl-δ-halo-γ-lactones with defined configurations of stereogenic centers. [...]
doi:10.3390/proceedings2019022047 fatcat:rjz6hscglnf6hgppmqa4dmsxom