Medicinal plants are said to have high nutritive value and as a result of that they are prescribed for their therapeutic values. Holoptelea integrifolia (Ulmaceae) is a versatile medicinal plant used in various indigenous system of medicine for curing diseases. Minerals are inorganic compounds needed by our body to regulate chemical reactions and maintain structures. In this present study, antimicrobial activity was done with the leaf extracts. The study revealed that the leaf extracts of

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... elea integrifolia is showed antimicrobial activity against Staphylococcus aureus and Escherichia coli, Aspergillus niger and Candida albicans. The phytochemical analysis also revealed the presence of Alkaloids, Flavonoids, Saponins, Phenols, Tannins, Glycosides, Anthraquinones, Terpenoids, Carbohydrates and Proteins. Larval mortality of Culex sps was observed after 24 h, 48 h and 72 h of exposure with four high concentrations of ethanolic leaf extract (1 ml, 2 ml, 3 ml and 4 ml) and five low concentrations of crude ethanolic leaf extract (100 ppm, 150 ppm, 200 ppm, 250 ppm and 300 ppm) of the plant. The percentage of mortality decreased with the decrease in the concentration of the test solutions. Minerals analysis of the seeds of Holoptelea integrifolia reveals that the seeds contain phosphorus, potassium, calcium, magnesium, sulphur, copper, iron and zinc.