Prevalence of Parasitic Infestation in Diabetic Patients in Tertiary Care Hospital

Dhruba Hari Chandi, Dhruba Hari Chandi, Sucheta J. Lakhani
2020 International Journal of Current Microbiology and Applied Sciences  
Especially in immunocompromised and immunosuppressive patient's infection of intestinal parasites are an important cause of morbidity and mortality worldwide. In developing countries this become as a major public health problem. Diabetes mellitus (DM) is a metabolic non-communicable disease characterized by hyperglycemia, caused by insufficient insulin secretion, action of impaired insulin or both. Many studies have been reported the problems of diabetics are increasing and have been reported
more » ... be immunocompromised. The main objective of this study is to determine the prevalence of parasites among DM patients. This is a cross-sectional study carried on diabetic patients who visit in the hospital. Total 110 DM patients were included in this study. Random patients were selected and fresh stool specimens were collected and processed in microbiology laboratory by Microscopy, Formalin-Ether Concentration and Modified Ziehl Neelsen staining techniques. Total 110 stool sample were collected. Among all 110 DM patients total 110 stool sample were process from which total 15(13.6%) sample were positive for parasite. Out of 110 patients 70(63.6%) were female and 40(36.4%) were male. In this study DM patients with the age range from 20 years to 70 years old were included with the mean age of 48.2 ±9.1years old [Standard Deviation (SD) is 13.1]. Between the age group 50-60 years old was more in number. Out of 110 samples 15(13.6%) were diagnosed as parasitic infection with one having mixed infection. Different parasites were identified as Entamoeba histolytica, Giardia lamblia, Ascaris lumbricoides & Cryptosporidium parvum with three protozoans and one helminthes. Most common parasite were Entamoeba histolytica 8(7.3%) followed by Cryptosporidium parvum 5(4.5%) Ascaris lumbricoides 2(1.8%) and Giardia lamblia (0.9%). In this study female 11 (15.7%) showed higher prevalence than male 4(10%). The age group 50 -60 years old showed the highest prevalence 5(14.3%). In this study Single and Mixed Parasitic Infections was also found in Diabetic Patients. In the mixed infection Entamoeba histolytica + Cryptosporidium parvum was found only in 1 patient and other as single infection in 14 patients. Single infections 14(12.7%) were more prevalent than mixed infections 1(0.9%). Entamoeba histolytica was found maximum as single infections. In this study the prevalence of parasitic infection among DM patients was 13.6%. There is increased risk of parasitic infection in DM patients especially with Entamoeba histolytica an opportunistic infection. The diagnosis of Cryptosporidium parvum indicates a weakened immune system in diabetic's patients. Hence for parasitic infection in DM patients should be screened routinely as stool examination for the social welfare.
doi:10.20546/ijcmas.2020.902.166 fatcat:hmrnbrefd5ddplxshazj6kxlzy