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Metabolomics and Inflammatory Mediator Profiling for the Differentiation of Life-Threatening and Non-Severe Appendicitis in the Pediatric Population
2021
Metabolites
While children with appendicitis often have excellent clinical outcomes, some develop life-threatening complications including sepsis and organ dysfunction requiring pediatric intensive care unit (PICU) support. Our study applied a metabolomics and inflammatory protein mediator (IPM) profiling approach to determine the bio-profiles of children who developed severe appendicitis compared with those that did not. Methods: We performed a prospective case-control study of children aged 0–17 years
doi:10.3390/metabo11100664
pmid:34677379
fatcat:ovuq5b5nqfajtpqmxius73hqli