Mediatorless N2incorporated diamond nanowire electrode for selective detection of NADH at stable low oxidation potential

Jayakumar Shalini, Kamatchi Jothiramalingam Sankaran, Huang-Chin Chen, Chi-Young Lee, Nyan-Hwa Tai, I-Nan Lin
2014 The Analyst  
The electrocatalytic properties of a N 2 incorporated diamond nanowire (N-DNW) unmodified electrode towards the oxidation of nicotinamide adenine dinucleotide (NADH) was critically evaluated. The electrochemical behavior of the N-DNW unmodified electrode was examined and compared with that of boron-doped diamond, glassy carbon electrode, and graphite electrodes. The N-DNW electrode had high selectivity and high sensitivity for the differential pulse voltammetric detection of NADH in the
more » ... of ascorbic acid at the lower and stable oxidation potential. Moreover, it exhibited strong stability after prolonged usage. The oxidation peak potential at the N-DNW electrode remained unchanged even after exposure to the solution, followed by washing, drying, and storage in laboratory air for 20 days, with minimization of surface contamination. Therefore, the N-DNW unmodified electrode shows promise for the detection of NADH and is attractive for use in a dehydrogenase based biosensor and other analytical applications.
doi:10.1039/c3an01246h pmid:24352298 fatcat:sloq65emmzb5tl7rito5hi5apy