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The expression of the antennal homoeotic mutant, Nasobemia, is shown to be strongly dependent on nutrition. Dietary deficiencies in any of the following: thiamine, calcium pantothenate, nicotinic acid or RNA, cause a curing of the homoeotic defect. It is demonstrated that the effects of thiamine and pantothenate are through limiting acetyl-CoA synthesis and that fatty acids are required for high penetrance of the Ns gene. Similar nutritional effects are described for other Antennapedia anddoi:10.1017/s0016672300019388 fatcat:kjpksckigvgqdkb3rz2ssgkp4e