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Effects of phospholipid unsaturation on the bilayer nonpolar region
2003
Journal of Lipid Research
Molecular dynamics simulations of two monounsaturated phosphatidylcholine (PC) bilayers made of 1-palmitoyl-2-oleoyl-PC (POPC; cis -unsaturated) and 1-palmitoyl-2-elaidoyl-PC (PEPC; trans -unsaturated) were carried out to investigate the effect of a double bond in the PC  -chain and its conformation on the bilayer core. Four nanosecond trajectories were used for analyses. A fully saturated 1,2-dimyristoyl-PC (DMPC) bilayer was used as a reference system. In agreement with experimental data,
doi:10.1194/jlr.m300187-jlr200
pmid:14594994
fatcat:o3jews4ygjef7g3ab6vcv4yav4