Inflammation is a common entity among chronic renal failure (CRF) patients. Neutrophil gelatinase-associated lipocalin (NGAL) is a member of lipocalin family and released from many tissues and cells. We aimed to investigate the relationship between serum NGAL levels and the inflammation markers such as high sensitive CRP (hs-CRP), Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) with different vascular access types used in dialysis patients. Methods: The study population included 90

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... patients and 30 healthy age-matched controls. The patients were divided into three groups (I, II, III) and group IV included the controls. In group I and II the patients were with central venous permanent catheter (CVPC) and arterio-venous fistula (AVF) respectively. Group III included 30 patients with CRF. Hemogram, biochemical assays, ferritin, IL-6, hs-CRP, TNF-α and NGAL were evaluated in all groups. Results: Serum NGAL levels were markedly higher in HD patients with CVPC than in with AVF (7645.80±924.61 vs 4131.20±609.87 pg/ml; p < 0.05). Positive correlation were detected between NGAL levels and duration of CVPC (r = 0.73, p = 0.000), TNF-α (r = 0.57, p = 0.00), hs-CRP (r = 0.80, p = 0.00), IL-6 levels (r = 0.691, p = 0.00) and ferritin (r = 0.32, p = 0.01), whereas serum NGAL levels were negatively correlated with serum albumin levels (r = -0.49, p = 0.00). In multiple regression analysis, duration of CVPC, hs-CRP and TNF-α were predictors of serum NGAL in HD patients. Conclusion: The inflammation was observed in HD patients and increases with CVPC. Our findings show that a strong relationship between serum NGAL levels and inflammation markers. NGAL may be used as a new marker for inflammation in HD patients. Objectives: To review the quality of education delivered to predialysis patients, presenting in either a planned or unplanned way, across one renal unit. To discover if patient choice is consistently offered, with particular focus on peritoneal dialysis (PD) and home haemodialysis (HHD). To determine if PD and HHD information is given accurately. To discover if treatment options education is ever revisited once dialysis therapy has been established.