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expression and that they identify speci®c MMP members as targets for novel therapeutics in the disease. Abbreviations: C T = cycle threshold; EAE = experimental autoimmune encephalomyelitis; HBECs = human brain-derived endothelial cells; IgG = immunoglobulin-G; MMP = matrix metalloproteinase; IFN-g = interferon-g; LPS = lipopolysaccharide; PBMC = peripheral blood mononuclear cell; PMA = phorbol-12,13-myristate acetate; TIMP = tissue inhibitor of metalloproteinases McCawley and Matrisian, 2001)doi:10.1093/brain/awg285 pmid:14506071 fatcat:jwhljihvynguvcixjx3g26pdru