A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

Yining Ji, Hongming Li, Alan M. Hyde, Qinghao Chen, Kevin M. Belyk, Katrina W. Lexa, Jingjun Yin, Edward C. Sherer, R. Thomas Williamson, Andrew Brunskill, Sumei Ren, Louis-Charles Campeau (+2 others)
2017 Chemical Science  
Detailed mechanistic studies of a Pd-catalyzed asymmetric C–N coupling led to a rational design of a new series of bis-phosphine mono-oxides ligated Pd(ii) pre-catalysts that allow for reliable and complete catalyst activation.
doi:10.1039/c6sc05472b pmid:28553522 pmcid:PMC5427683 fatcat:zqsn5s4prrej7ibq2bp3stn6ym