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BLAST is a widely used software toolkit for genomic sequence search. mpiBLAST is a freely available, open-source parallelization of BLAST that uses database segmentation to allow different worker processes to search (in parallel) unique segments of the database. After searching, the workers write their output to a filesystem. While mpiBLAST has been shown to achieve high performance in clusters with fast local filesystems, its I/O processing remains a concern for scalability, especially indoi:10.1145/1345206.1345262 dblp:conf/ppopp/BalajiFALKTM08 fatcat:jugxa4vmenhmjcgyqbikuqapru