From bench to bedside: Colistin nephrotoxicity and vitamin E

Omid Moradi, Zahra Sahraei, Sara Asadi
2019 Clinical Microbiology and Infectious Diseases  
oxidative stress have a role [24, 25] . Based on these data we thought to conduct a randomized trial to assess alpha-tocopherol effect on colistin nephrotoxicity in Loghman-Hakim hospital, a referral tertiary teaching medical center. Patients who are candidate to receive colistin to treat infections caused by multi-drug resistance gram negative bacillus are randomly assigned to receive 400 mg vitamin E in form of alpha tocopherol per day concomitantly by colistin or receive colistin alone. The
more » ... rial is registered in the Iranian Registry on Clinical Trials by the code of IRCT20130917014693N8. After finishing of the study results will be published.
doi:10.15761/cmid.1000161 fatcat:dwrqdr2r6vcrdnvdmtjs6cghle