The aim of the research was to develop guidelines and training materials to support the implementation of LOTO procedures in Industry 4.0. The analysis of manufacturing systems of Industry 4.0 showed that the requirements for LOTO procedures differ from those used in classical systems. The developed guidelines and training materials were verified during the pilot training. The mean value of the Likert scale score exceeds 4.4. The I-CVI index is mostly 1 and the lowest value is 0.86. Statistical

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... analysis using Student's t-test confirmed that the guidelines and training materials have excellent content validity at the 0.05 confidence level. This applies to their content, usefulness, comprehensiveness and completeness.