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Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry
A hand-held laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry (MS) method was developed for rapid screening of illegal substances in solid samples. To achieve that, a simple, inexpensive, battery-powered surgical laser diode at 940 nm was employed to ablate the solid samples. The potential of using a black polytetrafluoroethylene substrate to enhance the analytes' desorption to the gas phase was investigated and demonstrated. Among the optimized ESI parameters,doi:10.1021/acs.analchem.1c01083.s001 fatcat:f2kgbewcrjezrpzsqrfpee3wgm