A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
Tissue Transglutaminase and the Progression of Human Renal Scarring
Journal of the American Society of Nephrology
Experimental renal scarring indicates that tissue transglutaminase (tTg) may be associated with the accumulation of extracellular matrix (ECM), both indirectly via TGF-␤1 activation and directly by the formation of ⑀(␥-glutamyl) lysine dipeptide bonds within the ECM. The latter potentially accelerates deposition and confers the ECM with resistance to proteolytic digestion. Studied were 136 human renal biopsy samples from a range of chronic renal diseases (CRD) to determine changes in tTg anddoi:10.1097/01.asn.0000079614.63463.dd pmid:12874459 fatcat:hfrd3zm6djbvzo5n5vkeanwuja