Validation of In-Vitro Wound Healing Potential of Extracts of Pisonia grandis R.Br. Chick Chorio-Allantoic Membrane (CAM) Assay

2019 ijghc  
Pisonia grandis is a flowering tree of the Nyctaginaceae family, and is distributed throughout the coral cays of the Indian and Pacific Oceans. It is also commonly seen planted and reared in many households of the local areas of Coimbatore -one of the southern districts of Tamilnadu, India. The species often dominates mature coral cay vegetation, growing in dense stands up to 20 metres tall. Pisonia wood is rather weak and soft and decays rapidly when the trees fall. In continuation of our
more » ... es on validation of the medicinal potential of this plant, its in-vitro wound healing potential was assessed by chick chorioallantoic membrane (CAM) assay. The leaf petroleum ether extract of Pisonia grandis shows slightly higher percentage of blood vessel formation (50% increase) than the leaf ethanol extract (44%) whereas the dewaxed ethanol extract of leaves of Pisonia grandis express an equivalent decrease (44%). It may be proposed that the non-polar constituents of the non-polar extract of Pisonia grandis might play a greater role in stimulating angiogenesis than the constituents of the dewaxed leaf ethanol extract.
doi:10.24214/ijghc/hc/8/4/38489 fatcat:fkz2b46tuvgmfd62wgifedefky