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The development of atovaquone (ATQ)-resistant plasmodia strains suggests a need of new drugs for the mitochondrial bc 1 complex as drug target in protozoa. It was the aim of the study to establish a model consisting of submitochondrial particles (SMP) from yeast (mimicking the protozoal drug target) and bovine heart for the screening of compounds. Saccharomyces cerevisiae wild-type strains (W303-1A, DBY747) were grown on YPD-media at 30°C for three days. After harvesting the cells their celldoi:10.1186/1471-2210-7-s2-a56 fatcat:dzoioxfedjebxgz2237bywlzla