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Small RNAs are trafficked from the epididymis to developing mammalian sperm
RNAs present in mature mammalian sperm are delivered to the zygote at fertilization, where they have the potential to affect early development. The biogenesis of the small RNA payload of mature sperm is therefore of great interest, as it may be a target of signaling pathways linking paternal conditions to offspring phenotype. Recent studies have suggested the surprising hypothesis that the small RNA payload carried by mature sperm may include RNAs that were not synthesized during testiculardoi:10.1101/194522 fatcat:2b5dm3t63jf7dbptgfgxhviary