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This study concerns the development of a high performance workflow that, using grid technology, correlates different kinds of Bioinformatics data, starting from the base pairs of the nucleotide sequence to the exposed residues of the protein surface. The implementation of this workflow is based on the Italian Grid.it project infrastructure, that is a network of several computational resources and storage facilities distributed at different grid sites. Methods: Workflows are very common indoi:10.1186/1471-2105-6-s4-s19 pmid:16351745 pmcid:PMC1866389 fatcat:f67ts34yyvagpbgxkd667a2ajy