A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Genomic heterogeneity in tumors results from mutations and selection of high-fitness single cells, the operational components of evolution. Precise knowledge about mutational heterogeneity and evolutionary trajectory of a tumor can provide useful insights into predicting cancer progression and designing personalized treatment. The rapidly advancing field of single-cell genomics provides an opportunity to study tumor heterogeneity and evolution at the ultimate level of resolution. In thisdoi:10.1016/j.coisb.2017.11.008 fatcat:ynw5xltnvndghbajgpmhnjpmhy