P1-238: Exploration of multidisciplinary therapy including surgery in Limited Disease (LD) stage small cell lung cancer (SCLC): a clinical report of 122 cases from single institute

Yuankai Shi, Huijie Wang, Kelin Sun, Xiangru Zhang, Yan Sun
2007 Journal of Thoracic Oncology  
Objective: to analyse the follow-up results of treatment of small-cell lung cancer (SCLC) during period 1980-2005 years. There are many controversies about the surgical treatment of SCLC.On the other hand, other authors report a survival of 33% of five years in the first stage of the disease. Materials and Methods: In Thoracic Clinic of Institute of Oncology Vilnius University 2640 patients (pts) with lung cancer were treated surgicaly in the course of 1980-2005 years. In 220 cases small-cell
more » ... cases small-cell lung cancer was diagnosed. The distribution of pts according to TNM classification were: 6 pts had T1N0M0, 36pts-T2N0M0, 10pts -T3N0M0, 48pts -T1-2N1M0,12pts -T3N1M0, 60pts -T1,2N2M0, 5 pts-T4N1M0, 28pts -T4N2M0, in 15 pts distant metastases were detected after operation. The most common operation was lobectomy which have performed 79 pts, pneumonectomy -55, bilobectomy -26, segmentectomy, wedge resection-6 and in 54 cases was performed only explorative thoracotomy. In 4 cases tumor was removed during VATS surgery. 177 pts have received additional treatment (chemotherapy, radiotherapy), before surgery 50 pts and after operation -129. Some pts have received both methods of conservative treatment The satisfactory results were received in early stages of the disease, who were underwent lobectomy and received adjuvant therapy: median survival was 35.6 months. The pts after pneumonectomy lived 22.2 months. Conclusions: 1. The surgical treatment could perform only in cases of early stages (I-II) of small-cell lung cancer. 2. After operation intensive adjuvant chemotherapy(5-6 cycles) must be used in all cases (N0 and N+). The pts with N2 after chemotherapy must be treated with radiotherapy. 3. The staging of the tumor before surgery during surgical intervention is most important factor for suitabale treatment of pts with smallcell lung cancer P1-238 SCLC: Surgery Posters, Mon, Sept 3 Exploration of multidisciplinary therapy including surgery in Limited Disease (LD) stage small cell lung cancer (SCLC): a clinical report of 122 cases from single institute Supportive Care/QOL
doi:10.1097/01.jto.0000284336.05351.8e fatcat:vpmobt3xxjccbn7whcnvfau26u