Chronic Thromboembolic Pulmonary Hypertension Associated with Chronic Inflammation

Naoyuki Kuse, Shinji Abe, Hidehiko Kuribayashi, Asami Fukuda, Yuji Kusunoki, Ritsuko Narato, Hitoshi Saito, Akihiko Gemma
2016 Internal medicine (Tokyo. 1992)  
Chronic thromboembolic pulmonary hypertension (CTEPH) is one of the leading causes of severe pulmonary hypertension. According to previously reported studies in the pertinent literature, chronic inflammatory conditions may be implicated in the development of CTEPH. We herein describe the case of a 56-year-old woman who was diagnosed with CTEPH in association with chronic infection. The patient had experienced five episodes of pneumonia in the five years prior to the diagnosis of CTEPH. Blood
more » ... ts from the previous five years of outpatient follow-up demonstrated that the C-reactive protein level was slightly elevated. This case suggests that a relationship exists between chronic inflammation and CTEPH, and furthermore, may contribute towards elucidating the pathophysiology of CTEPH.
doi:10.2169/internalmedicine.55.5146 pmid:27250055 fatcat:26ndmxjfcbbetcdn6kk7x3s5ym