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Ethanolic extract of Annona muricata L., Annonaceae, leaf (AML) was used to investigate its antinociceptive and anti-ulcerogenic activities and the involvement of the mechanism of ethanolic leaves extract of AML in various animal models. Antinociceptive activity of AML extract was done using acetic acid-induced abdominal writhing in mice, formalin test in rats and hot plate test in mice. Furthermore, the antiulcerogenic effect of AML extract was studied in ethanol-induced ulcer model in rats,doi:10.1590/s0102-695x2012005000001 fatcat:3dspcadw5ff4nh2go3w2t3isvu