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Laeverin/aminopeptidase Q induces trophoblast invasion during human early placentation
2012
Human Reproduction
background: In primate placenta, extravillous trophoblast (EVT) invades maternal tissue in temporally-and spatially-regulated fashions. We previously identified a novel placenta-specific cell-surface aminopeptidase, laeverin/aminopeptidase Q, which is expressed on EVT-lineage cells in the fetal membrane. Laeverin possesses a peptide-binding site that is evolutionally unique to primates, suggesting possible involvement of laeverin in a primate-specific phenomenon during placentation. Thus, this
doi:10.1093/humrep/des068
pmid:22402206
fatcat:bm2xleqedbgznmrhnzcg5m7kqe