A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
Expression of HIF-1 in Injured Arteries Controls SDF-1 Mediated Neointima Formation in Apolipoprotein E Deficient Mice
Arteriosclerosis, Thrombosis and Vascular Biology
Objective-Hypoxia-inducible factor (HIF)-1␣ is the regulatory subunit of a transcriptional complex, which controls the recruitment of multipotent progenitor cells and tissue repair in ischemic tissue by inducing stromal cell-derived factor (SDF)-1␣ expression. Because HIF-1␣ can be activated under normoxic conditions in smooth muscle cells (SMCs) by platelet products, we investigated the role of HIF-1␣ in SDF-1␣-mediated neointima formation after vascular injury. Methods anddoi:10.1161/atvbaha.107.151050 pmid:17932320 fatcat:hu6lhvn3ofdofaajhwsgtre36e