Analysis of Binary Relations and Hierarchies of Enzymes in the Metabolic Pathways

Hiroyuki Ogata, Wataru Fujibuchi, Hidemasa Bono, Susumu Goto, Minoru Kanehisa
1996 Genome Informatics Series  
In conjunction with a new database system that efficiently organizes the metabolic pathway data from various organisms, we are developing computational methodologies using binary relations and hierarchies of enzymes. Biological knowledge integrated in the system includes genes, gene products, chemical compounds, enzyme reactions and metabolic pathway diagrams. By automatically mapping the enzymes of a specific organism on the pathway diagrams, it becomes possible to visualize the characteristic
more » ... features of the organismspecific metabolic pathways. With the aid of the computational methodology implemented in the system, it becomes again possible to analyze and investigate the pathways in terms of their function and evolution. In this paper, we describe the outline of the system and present new biological features of metabolic pathways revealed by the system.
doi:10.11234/gi1990.7.128 fatcat:qrtgq3ixz5eqrejkrl2jep6nby