Analysis of Surgically Treated Intraspinal Tumors in Southern Taiwan

Yu-Feng Su, Ann-Shung Lieu, Chih-Lung Lin, Kung-Shing Lee, Yen-Fen Hwang, Chun-Po Yen, Chih-Zen Chang, Joon-Khim Loh, Tzuu-Yuan Huang, Shiuh-Lin Hwang, Aij-Lie Kwan, Sheng-Long Howng (+1 others)
2007 Kaohsiung Journal of Medical Sciences  
In 1997, we presented an analysis of intraspinal tumors in south Taiwan [1] . In total, 120 cases of intraspinal tumors diagnosed and surgically treated at Kaohsiung Medical College Hospital between 1988 and 1995 were assessed, and the results were compared with those from other series. This previous study showed that the four most common histologic types of spinal tumors were nerve sheath tumors (40%), metastatic tumors (23.3%), meningiomas (11.7%) and neuroepithelial tumors (8.3%). The next
more » ... cade was marked by improved availability and quality of noninvasive imaging modalities, especially magnetic resonance imaging (MRI), which has facilitated diagnosis and management [2] . Because the age of the patient population in Taiwan is increasing rapidly [3], the epidemiology of spinal tumors may change. The purpose of this survey was to assess spinal tumor occurrence in Taiwan during a recent 5-year period and compare this assessment with the one we reported in 1997, and with those of other reported series. MATERIALS AND METHODS The medical histories of 117 consecutive patients who were surgically The medical records of 117 patients with spinal tumors who underwent surgery with pathologic confirmation from January 1999 to April 2004 at Kaohsiung Medical University Hospital were reviewed. Data from this review were compared with those obtained from the same institution 10 years earlier (covering the period 1988-1995) and from other reported series. There were 69 male and 48 female patients aged from 13 to 87 years old (mean age, 51.9). The most common pathologic findings were metastasis in 45.3% (53/117), nerve sheath tumors in 28.2% (33/117), meningiomas in 12% (14/117) and neuroepithelial tumors in 6% (7/117). The peak ages at diagnosis were 41-50 years and 61-70 years. A slight male predominance was noted for all tumors, except meningiomas. Motor weakness, even paralysis, was the major clinical presentation (64-86%), followed by sensory deficits (50%) and pain (42%). The location of tumors was most often in the thoracic (50.4%; 59/117), lumbosacral (27.4%; 32/117) and cervical spine (22.2%; 26/117) segments. Among the metastatic tumors, the lung (22.6%) and breast (15.1%) were the most common primary sites of origin, followed by unknown origin, the liver (hepatocellular carcinoma), the gastrointestinal tract and the nasopharynx (nasopharyngeal cancer).
doi:10.1016/s1607-551x(08)70005-6 pmid:18055306 fatcat:ymtuycuq5rb7hn6ewaykg5xcb4