Osteoarthritis and psoriatic arthritis: findings in three-dimensional biophotonics imaging

Zhen Yuan, Fong H Ieong, Huabei Jiang, Eric S Sobel
2014 Bio-medical materials and engineering  
The goal of this study is to capture the quantitative optical features of degenerative finger joints based on x-ray aided three-dimensional (3D) diffuse optical tomography (DOT). It is anticipated that the fused imaging technique can be applied to identifying the significant differences between osteoarthritis (OA) and psoriatic arthritis (PA). For a case study, total 6 subjects were selected to study the distal interphalangeal (DIP) finger joints. 2 OA patients, 2 PA patients and 2 healthy
more » ... and 2 healthy subjects were examined clinically first. Their DIP finger joints were then scanned by the multimodality imaging method. Our findings suggested that the developed multimodality imaging approach may aid to contradistinguish OA patients from PA patients with the healthy control, which is essential for a better diagnosis and treatment of inflammatory arthritis in humans.
doi:10.3233/bme-141128 pmid:25227015 fatcat:3plxtnz4svbu5ewa4igb2dek5e