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The cardiopulmonary bypass, or heart-lung machine is one of the biggest medical inventions in the mid -20th century and the advances in cardiac surgery would not have been possible without this contrivance. Nevertheless it is not without its share of side-effects, with post-perfusion acute lung injury being among one of the most severe and life-threatening complications. We report a case of 65-year-old female patient diagnosed with left main and three-vessel coronary artery disease and admitteddoi:10.35120/kij3404981i fatcat:wfljamavdrarho7qykt6nwprua