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The adaptive response of the archaeon Sulhlobus acidocaldarius BC65 to phosphate starvation was studied. When cells were subjected to phosphate limitation, their growth was affected. In addition, the levels of synthesis andlor the degree of phosphorylation of several proteins changed, as detected by two-dimensional nonequilibrium pH gradient electrophoresis of cells labelled in wivo with [35S]methionine and [35S]cysteine, or H, 3*P0,. After another growth-restricting treatment, a heat shock, adoi:10.1099/13500872-142-6-1531 pmid:8704993 fatcat:mqgh4toqevdaxowk2t7ouxpnha