Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip,Brassica, campestrisL.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice

Kiharu IGARASHI, Tsuyoshi MIKAMI, Yuri TAKAHASHI, Hideyo SATO
2008 Bioscience, biotechnology and biochemistry  
Isorhamnetin 3-O-glucoside, which was contained together with isorhamnetin 3,7-di-O-glucoside in atsumi-kabu leaves, suppressed increases in the plasma ALT and AST activities of mice with liver injury induced by the injection of carbon tetrachloride, but no suppression by isorhamnetin 3,7-di-O-glucoside was apparent. This result indicates that the release of glucose at the 7-position in isorhamnetin 3,7-di-Oglucoside was very important to mitigating liver injury.
doi:10.1271/bbb.70558 pmid:18323640 fatcat:77vhsp5mkjhc7fhr2uv37kljra