A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2023; you can also visit the original URL.
The file type is
Whether due to mutagens or replication errors, DNA mismatches arise spontaneously in vivo. Unrepaired mismatches are sources of genetic variation and point mutations which can alter cellular phenotype and cause dysfunction, diseases, and cancer. To understand how diverse mismatches in various sequence contexts are recognized and repaired, we developed a high-throughput sequencing-based approach to track single mismatch repair outcomes in vivo and determined the mismatch repair efficiencies ofdoi:10.1101/2023.01.08.523062 fatcat:sfpyrqkugnfjxfpe62b6w5rhem