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Zodiac: A Comprehensive Depiction of Genetic Interactions in Cancer by Integrating TCGA Data
2015
Journal of the National Cancer Institute
Genetic interactions play a critical role in cancer development. Existing knowledge about cancer genetic interactions is incomplete, especially lacking evidences derived from large-scale cancer genomics data. The Cancer Genome Atlas (TCGA) produces multimodal measurements across genomics and features of thousands of tumors, which provide an unprecedented opportunity to investigate the interplays of genes in cancer. Methods: We introduce Zodiac, a computational tool and resource to integrate
doi:10.1093/jnci/djv129
pmid:25956356
pmcid:PMC4554190
fatcat:a5n75kepnral5p6lg232yftema