Intracellular events and signaling pathways involved in sperm acquisition of fertilizing capacity and acrosome reaction

Elisabetta Baldi
2000 Frontiers in Bioscience  
TABLE OF CONTENTS 1. Abstract 2. Sperm capacitation: background 2.1. Modification in concentration of intracellular calcium and other ions during capacitation 2.2. Changes in membrane lipids and phospholipids during capacitation 2.3. Changes in protein phosphorylation and protein kinase activity during capacitation 2.3.1. Involvement of AC/cAMPPKA pathway in capacitation 2.3.2. Involvement of PKC in capacitation 2.3.3. Involvement of tyrosine phosphorylation in capacitation 3. Acrosome reaction
more » ... (AR): background 3.1. Intracellular calcium during acrosome reaction 3.2. Phospholipases activation during acrosome reaction 3.3. Activation of protein kinases during acrosome reaction process 4. DNA fragmentation in human spermatozoa 4.1. Origin of sperm DNA damage 5. Perspective 6. Acknowledgements 7. References
doi:10.2741/baldi pmid:11056077 fatcat:7t5qookshrgytj37l75dpfx3he