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BMC Systems Biology
Expansion of transcription factors is believed to have played a crucial role in evolution of all organisms by enabling them to deal with dynamic environments and colonize new environments. We investigated how the expansion of the Feast/Famine Regulatory Protein (FFRP) or Lrp-like proteins into an eight-member family in Halobacterium salinarum NRC-1 has aided in niche-adaptation of this archaeon to a complex and dynamically changing hypersaline environment. Results: We mapped genome-wide bindingdoi:10.1186/s12918-014-0122-2 pmid:25394904 pmcid:PMC4236453 fatcat:7cr3ugvw2vcfbhkjloud2tfjjm