Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors

Lu Guo, Gang Wang, Yuanming Feng, Tonggang Yu, Yu Guo, Xu Bai, Zhaoxiang Ye
2016 Radiation Oncology  
Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume definition in radiotherapy of brain tumors, and it presents the opportunities and challenges in the
more » ... tegration of multimodal functional MRI into clinical practice. The results indicate that specialized and robust post-processing algorithms and tools are needed for the precise alignment of targets on the images, and comprehensive validations with more clinical data are important for the improvement of the correlation between histopathologic results and MRI parameter images.
doi:10.1186/s13014-016-0702-y pmid:27655356 pmcid:PMC5031292 fatcat:33qjhv3jj5fdlpwqmzhn5zk6ji