A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a

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... ent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.