Effectiveness of the non-pharmaceutical public health interventions against COVID-19; a protocol of a systematic review and realist review

Shabnam Iezadi, Saber Azami-Aghdash, Akbar Ghiasi, Aziz Rezapour, Hamid Pourasghari, Fariba Pashazadeh, Kamal Gholipour, Wen-Jun Tu
2020 PLoS ONE  
Without any pharmaceutical intervention and vaccination, the only way to combat Coronavirus Disease 2019 (COVID-19) is to slow down the spread of the disease by adopting non-pharmaceutical public health interventions (PHIs). Patient isolation, lockdown, quarantine, social distancing, changes in health care provision, and mass screening are the most common non-pharmaceutical PHIs to cope with the epidemic. However, there is neither systematic evidence on the effectiveness of non-pharmaceutical
more » ... Is in controlling the COVID-19 nor on how these interventions work in different contexts. Therefore, in this study we will address two main objectives: 1) to assess the effectiveness of the non-pharmaceutical PHIs in controlling the spread of COVID-19 using a systematic review and meta-analyses; 2) to explore why, how, and for whom these interventions work using a realist review.
doi:10.1371/journal.pone.0239554 pmid:32991604 pmcid:PMC7523985 fatcat:gncmmpazejg2xi4ty52poveasa